Efficacy of magnesium sulfate in treatment of acute renal colic

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016020223552N6

Enrollment

100

Registered

2016-04-23

Start date

2014-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute renal colic. N20,N21,N22,N23

Interventions

Intervention 1: Intervention group: 15 mg/kg of magnesium sulfate 50 %( institute Pasteur.Tehran .Iran )with total volume 100 ml (dissolved in Normal saline) will be administered intravenously wi

Treatment - Drugs

Intervention group: 15 mg/kg of magnesium sulfate 50 %( institute Pasteur.Tehran .Iran )with total volume 100 ml (dissolved in Normal saline) will be administered intravenously within 15 minutes.

Control group : 100 ml of normal saline as placebo will be administered intravenously within 15 minute. in addition Treatment with the standard protocol of 0.1 mg/kg of morphine sulfate and 30 mg

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Clinical diagnosis of renal colic; aged between 18 and 55 years; VAS> 5. Exclusion criteria: A history of seizures, heart , liver, kidney or metabolic disease ; T > 38 ; systolic blood pressure< 90 mm Hg ; pregnancy; abdominal pain; opioid addiction ; use of calcium channel blocker .

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Arrival, 30 minutes and 60 minutes after injection. Method of measurement: VAS ruler.	—

Secondary

Measure	Time frame
Arterial oxygen saturation. Timepoint: At Arrival and 30 minutes and 60 minutes after injection. Method of measurement: Digital pulse oxymetery.;Systolic Blood Pressure. Timepoint: At Arrival and 30 minutes and 60 minutes after injection. Method of measurement: sphingmomonometer.;Diastolic Blood Pressure. Timepoint: At Arrival and 30 minutes and 60 minutes after injection. Method of measurement: sphigmomonometer.;Heart Rate. Timepoint: At Arrival and 30 minutes and 60 minutes after injection. Method of measurement: Pulse per minute.;Respiratory Rate. Timepoint: At Arrival and 30 minutes and 60 minutes after injection. Method of measurement: Respiration Per Minute.	—

Measure

Time frame

Arterial oxygen saturation. Timepoint: At Arrival and 30 minutes and 60 minutes after injection. Method of measurement: Digital pulse oxymetery.;Systolic Blood Pressure. Timepoint: At Arrival and 30 minutes and 60 minutes after injection. Method of measurement: sphingmomonometer.;Diastolic Blood Pressure. Timepoint: At Arrival and 30 minutes and 60 minutes after injection. Method of measurement: sphigmomonometer.;Heart Rate. Timepoint: At Arrival and 30 minutes and 60 minutes after injection. Method of measurement: Pulse per minute.;Respiratory Rate. Timepoint: At Arrival and 30 minutes and 60 minutes after injection. Method of measurement: Respiration Per Minute.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Abolfazl Jokar

Arak University of Medical sceinces

dr.a.jokar@gmail.com mabj_86@yahoo.com00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026