Graves. Thyrotoxicosis with diffuse goiter
Conditions
Interventions
Intervention 1: Intervention group: Fixed Low Dose (7 mCi)I-131/Single dose. Intervention 2: Intervention group: Fixed High Dose (15 mCi) I-131/Single dose. Intervention 3: Intervention group: Calcula
Treatment - Drugs
Intervention group: Fixed Low Dose (7 mCi)I-131/Single dose
Intervention group: Fixed High Dose (15 mCi) I-131/Single dose
Intervention group: Calculated Dose (100 micro Currie I-131/gr Thyroid tissue) / Single dose
Intervention group: Calculated Dose (150 micro Currie I-131/gr Thyroid tissue) / Single dose
Intervention group: Calculated Dose (200 micro Currie I-131/gr Thyroid tissue) / Single dose
Intervention group: Calculated Dose (300 micro Currie I-131/gr Thyroid tissue) / Single dose
Sponsors
Mashhad University of Medical Sciences, Vice chancellor for research
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age more than 18; Confirmed cases of Graves' disease; No previous history of radioiodine therapy;No previous history of thyroid surgery Exclusion criteria: pregnancy; lactation; severe ophtalmopathy; no desire to join to study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TSH, T3, T4. Timepoint: 1,3,6,12 months post radioiodine therapy. Method of measurement: Blood test.;Thyroid volume. Timepoint: 1,3,6,12 months post radioiodine therapy. Method of measurement: Ultrasonography.;Thyroid weight. Timepoint: 1,3,6,12 months post radioiodine therapy. Method of measurement: Physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Narjess Ayati
Ghaem Nuclear Medicine Reserch Center
Outcome results
None listed