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The effect of rehabilitation and Vit. D co-adminitration on the treatment of vestibular neuritis

Effects of vestibular rehabilitation and 25-Hydroxyvitamin D co-administration on vestibular function and postural control in patients with vestibular neuritis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160131026279N7
Enrollment
44
Registered
2025-11-26
Start date
2024-09-29
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vestibular neuritis. Vestibular neuronitis, unspecified ear

Interventions

Intervention 1: Intervention group (VRT+VITD): receiving an individualized program for 30 minutes, 3 times a day for 6 weeks, based on their complaints. Exercises include
gaze stabilization (VOR adaptation and substitution exercises), vestibule-spinal reflex stabilization, and habituation exercises. In addition, the patient will receive 50000 Units of 25-Haydroxy VitD
gaze stabilization (VOR adaptation and substitution exercises), vestibule-spinal reflex stabilization, and habituation exercises.

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Diagnosed with vestibular neuritis (VN) Caloric weakness = 25 No previous experience with vestibular exercises or rehabilitation therapy Age range from 30 to 60 years No history of previous vestibular disorder (vertigo/dizziness) Lack of drug consumption which results in suppressing vestibular compensation Lack of musculoskeletal problems that impair gait Lack of VitD supplementation, osteomalacia, or osteoporosis treatment. Serum VitD deficiency (<21 micro IU) Willingness to participate in the study

Exclusion criteria

Exclusion criteria: Diagnosed with diabetes (Type-2), vision problems, neurologic disorder, schizophrenia, bipolar disorder, or major depression, any systemic or chronic diseases disturbing Vitamin D metabolism such as chronic renal failure, chronic liver disease, or hormonal disorders receiving corticosteroid therapy Drug or alcohol addiction Contraceptive consumption, pregnancy, lactation, or menopause in women Cognitive impairment

Design outcomes

Primary

MeasureTime frame
Vestibulo-ocular reflex gain. Timepoint: Before and after intervention. Method of measurement: Video head impulse test.;Displacement of center of pressure. Timepoint: Before and after intervention. Method of measurement: Forceplate.;Velocity of center of pressure displacement. Timepoint: Before and after intervention. Method of measurement: Forceplate.

Secondary

MeasureTime frame
Covert and overt saccades. Timepoint: Before and after intervention. Method of measurement: Video head impulse test.;Mean total velocity of center of pressure displacement. Timepoint: Before and after intervention. Method of measurement: Forceplate.;Area of center of pressure displacement. Timepoint: Before and after intervention. Method of measurement: Forceplate.;Dizziness Handicap Inventory score. Timepoint: Before and after intervention. Method of measurement: Dizziness Handicap Inventory.;Vertigo Symptom Scale-short form score. Timepoint: Before and after intervention. Method of measurement: Vertigo Symptom Scale-short form.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMansoureh Adel Ghahraman

Tehran University of Medical Sciences

madel@tums.ac.ir+98 21 7753 4364

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026