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Effectiveness of intravenous fentanyl in opioid user patients with limb trauma

Comparison between intravenous morphine versus fentanyl efficacy in acute pain relief in drug abuser patients with pain due to acute limb traumatic injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201601308872N10
Enrollment
320
Registered
2016-02-13
Start date
2016-02-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury, poisoning and certain other consequences of external causes. Fracture of upper limb, level unspecified, Other injuries of upper limb, level unspecified, Fracture of lower limb, level unspecified, Other injuries of lower limb, level unspecified

Interventions

Intervention 1: Intervention group (B) receive 1 micro/kg intravenous fentanyl. Intervention 2: Group A receive intravenous morphine sulfate 0.1 mg/kg.
Treatment - Drugs
Intervention group (B) receive 1 micro/kg intravenous fentanyl
Group A receive intravenous morphine sulfate 0.1 mg/kg

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: age above 18; limb injury;Glasgow coma scale above 14; pain intensity above 5 cm according to visual analogue scale(VAS); past history of opioid usage and history of usage in last week; hemodynamic stability. Exclusion criteria: decrease level of consciousness during drug injection; history of chronic illness( asthma, congenital or acquired heart disease, chronic liver disease, billiary disease, chronic kidney and lung disease); allergy to fentanyl and morphine; lack of cooperation in study process; opioid consumption after acute limb traumatic injury

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain level of patients. Timepoint: 0,5,15,30,60. Method of measurement: visual analoge scale.

Secondary

MeasureTime frame
Drug complications. Timepoint: After drud prescription. Method of measurement: ABSEVATION AND PATIENT COMPLAIN.;Patient satisfaction. Timepoint: After pain control. Method of measurement: beck questionary.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHojat Sheikh Motahar Vahedi

Tehran University of Medical Sciences

vahedihojat@yahoo.com+98 21 8490 2719

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026