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The effects of propofol on transureteral lithotripsy(TUL)

The effects of propofol on transureteral lithotripsy(TUL)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201601296803N10
Enrollment
120
Registered
2016-04-10
Start date
2012-04-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Calculus of ureter. Ureteric stone

Interventions

Intervention 1: Administration of midazolam 0.02 mg/kg and fentanyl 2 µg/kg and induction with hypnotic, propofol 2.5 mg/kg. Intervention 2: Administration of midazolam 0.02 mg/kg and fentanyl 2 µg/kg
Treatment - Drugs
Administration of midazolam 0.02 mg/kg and fentanyl 2 µg/kg and induction with hypnotic, propofol 2.5 mg/kg
Administration of midazolam 0.02 mg/kg and fentanyl 2 µg/kg and induction with hypnotic, Nesdonal 5mg/kg

Sponsors

Vice chancellor for research, Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: signing written Informed consent, ASA class ?-??, Age between 15 and 45 years, Elective surgery, patients with lower ureteral stones smaller than 20 mm. Exclusion criteria: 1- history of renal colic 2-history of renal stone expulsion3-history of renal anatomic or functional disorders 4- history of TUL 5- history of difficult intubation 6-history of pulmonary disease 7-history of cigarette smokingr8-history of drug abuse 9-history of NSAIDs and corticosteroid medication 10-pregnancy 11-hypersensitivity to propofol 12-hypersensitivity to egg or soy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Decreasing ureter spasm. Timepoint: update once, during surgary. Method of measurement: increase succes rate in ureteroscopy and tul.

Secondary

MeasureTime frame
Time of TUL. Timepoint: once, during surgEery. Method of measurement: Recorded in the questionnaire.;Rate of need for ESWL. Timepoint: once, during surgery. Method of measurement: Recorded in the questionnaire.;Rate of need for ureter stent. Timepoint: once, during surgery. Method of measurement: update Recorded in the questionnaire.;Rate of the need for DJ. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of need for ureter catheter. Timepoint: once, during surgery. Method of measurement: Recorded in the questionnaire.;Rate of ureter evulsion. Timepoint: once, during surgary. Method of measurement: update Recorded in the questionnaire.;Rate of Acute pyelonephritis. Timepoint: after surgery. Method of measurement: Recorded in the questionnaire.;Success rate of stone removal. Timepoint: update once, during surgery. Method of measurement: Recorded in the questionnaire.;Systolic blood pressure. Timepoint: before induction of anesthesia, 1 min and 5min after induction. Method of measurement: mm-Hg and record in questionnaire.;Diastolic blood pressure. Timepoint: before induction of anesthesia, 1 min and 5min after induction. Method of measurement: mm-Hg and record in questionnaire.;Heart rate. Timepoint: before induction of anesthesia, 1 min and 5min after induction. Method of measurement: beat per minute and Recorded in the questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbolfazl Firouzian MD

Mazandaran University of Medical Sciences

A.firouzian@mazums.ac.ir; Ab.firouzian@gmail.com+98 11 3337 5038

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026