stroke. Stroke, not specified as haemorrhage or infarction
Conditions
Interventions
Intervention 1: Intervention group: Infusion of citicoline 1 gr in normal saline (overall 20 ml) once daily for 10 days. Intervention 2: Control group: Infusion of 20 ml normal saline once daily for 1
Treatment - Drugs
Placebo
Intervention group: Infusion of citicoline 1 gr in normal saline (overall 20 ml) once daily for 10 days
Control group: Infusion of 20 ml normal saline once daily for 10 days
Sponsors
Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (a) age of 18 to 85 years; (b) acute stroke; (c) NIHSS score between 6 to 22. Exclusion criteria: (a) previous history of stroke; (b) renal or liver failure; (c) cancer; (d) active infectious disease during last month; (e) trauma or surgery during last month; (f) history of collagen vascular disease; (g) immunosuppressive medications or corticosteroid; (h) signs of brain hernia; (i) convulsion at the time of stroke; (j) neurologic disease or dementia; (k) pregnancy or breastfeeding; (l) receiving vasodilator medications.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measuring stroke score (NIHSS ). Timepoint: at baseline and 10 and 90 days after intervention. Method of measurement: based on NIHSS.;Measuring stroke score (Barthel Index). Timepoint: at baseline and 10 and 90 days after intervention. Method of measurement: based on Barthel Index.;Measuring stroke score (Modified Rankin Scale). Timepoint: at baseline and 10 and 90 days after intervention. Method of measurement: based on Modified Rankin Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Shahir Mazaheri
Sina Hospital
Outcome results
None listed