Premedication effect of intranasal midazolam and dexmedetomidine on children behavior

Comparison of intranasal midazolam and dexmedetomidin premedication effect on 2-6 years old uncooperative children behavior in dentistry

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201601281882N7

Enrollment

Registered

2016-03-13

Start date

2016-02-13

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety. Organic anxiety disorder

Interventions

Intervention 1: Dexmedotimidine 1µg/kg, intranasal. Intervention 2: Midazolam 0.2 mg/kg, intranasal.

Treatment - Drugs

Dexmedotimidine 1µg/kg, intranasal

Midazolam 0.2 mg/kg, intranasal

Eligibility

Sex/Gender

All

Age

2 Years to 6 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Healthy 2-6 years old children? Uncooperative negative and definitely ranked as Frankel scale? having at least two sessions dental treatment Exclusion criteria: Cold and allergy?Tonsils hypertrophy more than 50%? severe obesity

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Conscious sedation. Timepoint: Every 15 minutes. Method of measurement: Houpt scale.	—

Secondary

Measure	Time frame
SpO2. Timepoint: Every 15 minutes. Method of measurement: pulse ooxymeter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLily Shafie

Shahid Beheshti Dental School

lshafie2004@yahoo.com+98 21 2240 3010

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026