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Celexib and Peregabalin effect on pain after Orthopedic surgery.

A clinical trial comparing preoperative prescription of two drugs Celexib and Peregabalin on postoperative pain in patients volunteer Orthopedic surgery.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016012715281N5
Enrollment
120
Registered
2016-08-06
Start date
2016-06-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The pain after Orthopedic surgeries.. Other Complication of Orthopedic surgeries.

Interventions

Intervention 1: The control group: The first group
10 mL of 0.9% Normal Saline IV through Angiocatheter
Three hours before entering the Operation room. Intervention 2: The intervention group: The second group
Celexib of abooreihan factory with the dose of 200 mg orally
Three hours before entering the Operation room. Intervention 3: The intervention group: The group third
Peregabalin of abooreihan factory with the dose of 150 mg orally
Three hours before entering the Operation room.
Placebo
Treatment - Drugs
The control group: The first group
The intervention group: The second group
The intervention group: The group third

Sponsors

Vice chancellor for research, Shiraz University of Medical Sciences (International Branch)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Volunteer Orthopedic surgery patients between 18 and 65 years. Exclusion criteria: People under 18 and over 65 years; Drug addicts; Diabetics; Patients with Cardiovascular Disorders; Patients who are taking Steroids for any reason; Patients who are taking Nonsteroidal anti-inflammatory drugs ongoing; Pregnant women; Patients who are taking Antidepressant and Antipsychotic drugs; Patients with fractures of the femor and pelvis.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain level after Orthopedic surgery. Timepoint: The pain is investigated 45 minutes after the end of anesthesia in the recovery room and three hours after entering the ward. Method of measurement: Visual and intrrogative measure of pain from the patient and complete the questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Seyed Ebrahim Sadeghi

Shiraz University of Medical Sciences

seyedebrahims@yahoo.com+98 71 4334 5705

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026