Erosive lichen planus. Other lichen planus
Conditions
Interventions
Intervention group: the patient will be given a dose of 0.5 to 1 mg per kg prednisolone daily for seven days followed by a reduction of 5 mg each subsequent day..
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Suffering from oral erosive lichenoid reaction that has been definitely diagnosed by histopathologic diagnosis The patient has consent to participate in the study
Exclusion criteria
Exclusion criteria: Presence of systemic and inflammatory disease (e.g. Covid disease, blood system malignancies, etc.) that affects study factors (LDH, CRP) The patient had been receiving former treatment for the study lesion Presence of another lesion in the patient's mouth
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The measure of salivary lactate dehydrogenase. Timepoint: measurement of lactate dehydrogenase just before the beginning of systemic treatment and 14 and 28 days after beginning the use of systemic corticosteroid. Method of measurement: Non-stimulating saliva sampling.;The measure of salivary C Reactive Protein. Timepoint: measurement of C Reactive Protein just before the beginning of systemic treatment and 14 and 28 days after beginning the use of systemic corticosteroid. Method of measurement: Non-stimulating saliva sampling. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Saberi
Esfahan University of Medical Sciences
Outcome results
None listed