spinal anesthesia induced hypotension. Other complications of spinal and epidural anaesthesia during labour and delivery
Conditions
Interventions
Intervention 1: Intervention1: after performing spinal anesthesia (with 10 milligram bupivacaine plus 25 micro-gram fentanyl) 100 microgram phenylephrin in 1 cc volume will be injected and then infus
Treatment - Drugs
Intervention1: after performing spinal anesthesia (with 10 milligram bupivacaine plus 25 micro-gram fentanyl) 100 microgram phenylephrin in 1 cc volume will be injected and then infusion of normal sa
Intervention 2: after performing spinal anesthesia (with 10 milligram bupivacaine plus 25 micro-gram fentanyl) normal saline in 1 cc volume will be injected and then infusion of phenylephrine 50 m
Control group: after performing spinal anesthesia (with 10 milligram bupivacaine plus 25 micro-gram fentanyl) normal saline in 1 cc volume will be injected and then infusion of normal saline will be
Sponsors
Vice chancellor for Research and Technology, Hamadan University Of Medical Sciences
Eligibility
Sex/Gender
Female
Age
16 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: All of the ASA 1 healthy term parturients referring to Fatemieh hospital candidate for Cesarean section were included in the study. Exclusion criteria: chronic hypertension; pre eclampsia; twin pregnancy;, preterm labor; allergy to drugs; cardiovascular disease; renal disease and previous abdominal surgeries with adhesion band and fibrosis.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spinal anesthesia induced blood pressure change. Timepoint: before performing spinal anesthesia, every 2 minutes until delivery and then every 5 minutes until the end of surgery. Method of measurement: blood pressure was measured with automatic blood pressure device and hypotension was defined as more than 20% decrease of BP compared to baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate. Timepoint: before performing spinal anesthesia and then every 5 minutes until the end of surgery. Method of measurement: Electrocardiogram monitoring.;Nausea. Timepoint: every 5 minutes until the end of surgery. Method of measurement: observation.;Vomiting. Timepoint: every 5 minutes until the end of surgery. Method of measurement: observation.;Rescue vasopressor dose. Timepoint: at the end of surgery. Method of measurement: measurement.;Neonatal condition. Timepoint: at min 1 and 5. Method of measurement: Apgar score mesurements by observation and physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahshid Nikooseresht M.D
Hamadan University of Medical Sciences
Outcome results
None listed