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Effect of concentration of irrigants on endodontic postoperative pain

The effect of irrigation with two concentration of sodium hypochlorite on postoperative pain following single-visit endodontic treatment: A triple blinded randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201601202016N6
Enrollment
100
Registered
2016-01-24
Start date
2016-01-15
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible Pulpitis. Pulpitis

Interventions

Intervention 1: Intervention: 2.5% sodium hypochlorite will be used for irrigation during root canal preparation. Between instrumentation with each file to the next instrument, the root canals will
Treatment - Other
Treatment - Drugs
Intervention: 2.5% sodium hypochlorite will be used for irrigation during root canal preparation. Between instrumentation with each file to the next instrument, the root canals will be rinsed with 2
Control: 5.25% sodium hypochlorite will be used for irrigation during root canal preparation. Between instrumentation with each file to the next instrument, the root canals will be rinsed with 2m

Sponsors

Vice Chancellor for Research and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: no systemic disease; first and second mandibular molar with irreversible pulpitis; normal preapical radiography; mild sensitivity to percussion; no or mild pretreatment pain; having no medication at least 6 hours before the treatment visit; age at least 18 years old; no allergic reaction to the lidocaine with epinephrine 1:80000, gelofen, and sodium hypochlorite. Exclusion criteria: pregnancy and lactation; severe periodontal diseases; over instrumentation or overfilling; teeth that cannot be isolated; root canal calcification; root resorption; and the teeth that cannot be restored.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Postoperative pain. Timepoint: Six, 12, 24, 48, 72 hours and 4, 5, 6, 7 days following the treatment. Method of measurement: Visual analogue scale.

Secondary

MeasureTime frame
Analgesic consumption. Timepoint: 6, 12, 24, 48, 72 hours and 4, 5, 6, 7 days following the treatment. Method of measurement: Using a specific form.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Arash Shahravan

Endodontology Research Center

arashahravan@gmail.com+98 343212065

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026