advising of high doses interalipid.
Conditions
Interventions
Intervention 1: Control group: this group started with an injectable lipid emulsion from 1 gr / kg per 24 hours and increase 1 gram daily to 3 grams per kilogram per 24 hours . We monitor neonate with
Sponsors
Vice chancellor for research of Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 28 Days
Inclusion criteria
Inclusion criteria: All children born in Akbar Abadi Hospital with a birth weight of less than 1500 grams. Had no perinatal asphyxia (Apgar 5 minutes below 6). Parents had a written consent for entry into the study. Had no major anomalies.
Exclusion criteria
Exclusion criteria: If there is any evidence of sepsis before randomization If there is any evidence of metabolic acidosis before randomization hypoxia less than 90% before randomization
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Triglyceride. Timepoint: Before the intervention, then twice a week. Method of measurement: laboratory kit.;Arterial blood gas analysis and blood bicarbonate. Timepoint: Before the intervention, then twice a week. Method of measurement: laboratory kit.;Blood glucose. Timepoint: Before the intervention and then daily. Method of measurement: laboratory kit.;Neonate weight. Timepoint: Before the intervention and then daily. Method of measurement: Scales.;CRP. Timepoint: Before the intervention, then twice a week. Method of measurement: laboratory kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood culture. Timepoint: Before intervention and then if symptoms of sepsis occur. Method of measurement: Observation of microbial growth in culture media. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMandana Kashaki
Iran University of Medical Sciences
Outcome results
None listed