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The effect of propolis and nanohydroxyapatite in treatment of dentinhypersensivity.

A comparative efficacy of 50% ethanol extract of propolis , composition of 50% ethanol extract of propolis and nanohydroxyapatite and placebo in dentinal hypersensivity treatment : adouble blind study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016011911888N2
Enrollment
55
Registered
2016-05-03
Start date
2015-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin Hypersensivity. Other specified diseases of hard tissues of teeth

Interventions

Intervention 1: Second intervention group: composition of 50% ethanol extract of propolis and nanohydroxy apatite. Intervention 2: First intervention group: 50% ethanol extract of propolis. Interventi
Treatment - Drugs
Placebo
Second intervention group: composition of 50% ethanol extract of propolis and nanohydroxy apatite
First intervention group: 50% ethanol extract of propolis
Third intervention group: placebo

Sponsors

Shahid Sadoughi Dentistry Faculty
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria were patients who attended in Dental School of Shahid sadoughi University of Medical Sciences, Yazd, Iran, sensitive teeth with signs of abrasion, erosion or cervical dentin’sexposure. Exclusion criteria were teeth with evidence of pulpitis, caries lesions, defective restorations, enamel’s crack, active periodontal disease, decay or deterioration in the cervical area that needs to class V fillings, cracked or endodontically treated teeth; teeth with large restoration; fixed prosthesisor as abutmentof removable prosthesis; daily intake of anti-inflammatory drugs, analgesics, tooth desensitizer; patients with surgical periodontal ororthodontic treatment in the last 3 months; suppressed immune systems; pregnant and lactating patients; systemic conditions is caused or predictive factor for DH or too much acidic diet.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Before intervention, 2 and 4 weeks after intervention. Method of measurement: Visual analog scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Motahare Amiri

Shahid Sadoughi Dentistry Faculty

motahare_amiri@yahoo.com+98 35 3625 5881

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026