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Comparison of sedative and analgesic effect of Gabapentin and Dexmedetomidine

Comparison of sedative and analgesic effect of Gabapentin and Dexmedetomidine in patients undergoing laparoscopic surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016011822794N2
Enrollment
40
Registered
2016-03-13
Start date
2016-04-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety. Other mental disorders due to brain damage and dysfunction and to physical disease

Interventions

Intervention 1: The first group gabapentin, 300 mg one hour before surgery. Intervention 2: The second group Dax medetomidine 0.5-1 micrograms per patient weight in the morning before surgery.
Treatment - Drugs
The first group gabapentin, 300 mg one hour before surgery
The second group Dax medetomidine 0.5-1 micrograms per patient weight in the morning before surgery

Sponsors

Vice Chancellor for research of Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Entry criterion: Age between 18 and 65 ASA1, 2 Body mass index lower than 28 kg on stature product Acquire written consent Exit criterion: Existence of records in a systemic malady (high blood pressure, all types of collagen disease, ischemic heart, kidney, digestive system and etc…), allergies records, contraindications of gabapentin and dexmedetomidine Addiction to drugs and alcohol Pregnancy Paroxysmal

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Anxiety. Timepoint: 6 hours after intervention. Method of measurement: Ramsay scale.;Pain. Timepoint: 6 hours after intervention. Method of measurement: standard questionnaires VAS.

Secondary

MeasureTime frame
Sleep without provocation. Timepoint: 6 hours after intervention. Method of measurement: Ramsay scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbolfazl Abdollahpoor

Semnan University of Medical Sciences

felordce@yahoo.com+98 23 3343 7859

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026