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The effect of Topical Ointment on the Process of Wound Healing

Clinical Evaluation of Topical Nanocomplex ointment on Chronic venous ulcers: A double-blind randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160118026096N3
Enrollment
60
Registered
2021-08-22
Start date
2021-03-10
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wound Healing.

Interventions

Intervention 1: Intervention group: The intervention group in this study is a randomly selected 30-person group that uses an alternative medicine to improve the wound healing process. Surgery by a ge

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age range 30 to 60 years Have referred for the treatment of chronic venous ulcers. The lesion is clinically benign.6.

Exclusion criteria

Exclusion criteria: The lesion is clinically malignant. The ability to create keloids or scars due to injuries Previous or current history of scroderma History of radiotherapy treatment Immunosuppressive use or defective immune system Pregnancy or breastfeeding Patient dissatisfaction with continued use of ointment

Design outcomes

Primary

MeasureTime frame
En Wound Surface. Timepoint: Day one (surgery day), Day 4, 7 and 14 after surgery. Method of measurement: Wound healing is evaluated by measuring the wound surface, the percentage of wound healing, and the length of time needed for closure and complete repair of the wound. The surface of the wound is measured on days 1, 4, 7 and 14 after the surgery with Ferguson and Logan method. This is accomplished by placing the transparent paper on the wound and draw the wound shape. Then the transparent paper is transferred to the millimeter lattice paper and counted.

Secondary

MeasureTime frame
Wound resizing. Timepoint: The wound surface is digitally photographed on days 1, 7 and 14 after surgery. Method of measurement: The wound surface is digitally photographed on days 1, 7 and 14 after surgery.The wound surface is then measured with Image J software.;Inflammation rate. Timepoint: On days 1, 7 and 14, the amount of inflammation is determined by the doctor. Method of measurement: Determination of inflammation by a doctor 0-3 score(none- mild- moderate- severe).;Determining the amount of pain. Timepoint: On days 1, 7 and 14, the patient is asked about the amount of pain by the doctor. Method of measurement: Based on patient questions and classification 0-10 score *(no pain 0 / mild pain 1-3/ moderate pain 4-6 / severe pain 7-9 / worst pain 10).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasrin Takzaree

Tehran University of Medical Sciences

takzaree@tums.ac.ir+98 21 8895 3008

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026