Comparing the effect of fentanyl, sufentanil and alfentanil on hemodynamic changes after tracheal intubation in opiate addicted patients.

Comparing the effect of fentanyl, sufentanil and alfentanil on cardiovascular response after tracheal intubation in opiate addicted patients after elective surgeries.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016011721383N4

Enrollment

Registered

2016-03-13

Start date

2016-01-13

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular response. Acute Chagas disease with heart involvement

Interventions

Intervention 1: Administration of alfentanil 20 microgram per kilogram of body weight before induction of anesthesia. Intervention 2: Administration of fentanyle 2 microgram per kilogram of body weigh

Prevention

Administration of alfentanil 20 microgram per kilogram of body weight before induction of anesthesia.

Administration of fentanyle 2 microgram per kilogram of body weight before induction of anesthesia.

Administration of sufentanil 0.2 microgram per kilogram of body weight before induction of anesthesia

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: all opiate addicted patients who were scheduled to undergo elective surgeries with tracheal intubation. Exclusion criteria: hypertension; non elective surgeries; diabetes mellitus; dysautonomia; heart failure; severe hemorrhage; severe hemodynamic instability.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Before induction of anesthesia, 3 minutes after induction of anesthesia, after intubation. Method of measurement: In mmhg with digital manometer.;Heart rate. Timepoint: Before induction of anesthesia, 3 minutes after induction of anesthesia, after intubation. Method of measurement: Beat per minute with electrocardiography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Amir Saber Tanha

Birjand University of Medical Sciences

amirsaber63@gmail.com+98 56 3243 2778

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026