Investigating the effect of chewing gum containing postbiotic on the number of Streptococcus mutans bacteria in saliva

Production and investigation of antibacterial effects of chewing gum containing postbiotic yeast Saccharomyces boulardi and its chewing effect on Streptococcus mutans levels in human saliva: a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160117026069N10

Enrollment

Registered

2024-01-27

Start date

2024-01-27

Completion date

Unknown

Last updated

2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental decay. Dental caries

Interventions

Intervention 1: Control group: Normal gum, twice a day for ten days. Intervention 2: Intervention group: Gums containing postbiotic, twice a day for ten days. Intervention 3: Control group: Gums conta

Eligibility

Sex/Gender

All

Age

15 Years to 40 Years

Inclusion criteria

Inclusion criteria: All adults between 15 and 40 years old

Exclusion criteria

Exclusion criteria: People who have been treated with antibiotics within two weeks before the start of the study Individuals with any active dental or gum disease within two weeks prior to the start of the study People who are allergic to any of the gum compounds

Design outcomes

Primary

Measure	Time frame
Streptococcus mutans bacteria count in saliva. Timepoint: Before the study, ten days after the study. Method of measurement: Culture and bacterial count.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHadi Pourjafar

Karaj University of Medical Sciences

pourjafarhadi59@gmail.com+98 26 3464 3705

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026