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Comparitive prophylactic effect of pregabalin versus aminophylline plus dexamethasone in preventing postdural puncture headache in caesarian delivery.A double blind clinical trial.

Comparitive prophylactic effect of pregabalin versus aminophylline plus dexamethasone in preventing postdural puncture headache in caesarian delivery.A double blind clinical trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201601161936N16
Enrollment
300
Registered
2016-02-22
Start date
2015-03-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prophylactic effect of pregabalin versus aminophylline plus dexamethasone in preventing postdural puncture headache. Soft tissue disorder, unspecified

Interventions

Intervention 1: Group C received saline (placebo) i.v in similar volume of dexamethasone plus aminophylline and the oral placebo capsule 3 times a day. Intervention 2: Group P(pregabaline ) receive 1
Treatment - Drugs
Group C received saline (placebo) i.v in similar volume of dexamethasone plus aminophylline and the oral placebo capsule 3 times a day
Group P(pregabaline ) receive 100mg oral pregabaline capsule 3 times a day (each 8 hour) before onset of headache and saline i.v. in similar volume of dexamethasone plus aminophylline as placebo for b
Group A(aminophylline plus dexamethasone) receive aminophylline 1.5 mg/kg i.v. plus dexamethasone 0.1 mg/kg i.v and a placebo oral capsule similar in shape to the pregabaline 3 times a day thirty m

Sponsors

Bushehr University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: all patients who are candidates for elective cesarian and age between 18 -45. Exclusion criteria: history of sensitivity to medication; chronic headace and any condition that contraindicate spinal anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Post spinal headace. Timepoint: Two weeks. Method of measurement: Question.

Secondary

MeasureTime frame
Patient satisfication. Timepoint: Two weeks. Method of measurement: Question.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Abdolreza Najafi Anaraki

Bushehr University of Medical Sciences

arna566@yahoo.com+98 77 3354 0088

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026