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Comparison of the adding of dexmedetomidine to paracetamol or ketorolac for analgesia after caesarean

Comparison of the adding of dexmedetomidine to paracetamol or ketorolac for analgesia after caesarean

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201601147984N24
Enrollment
60
Registered
2016-07-01
Start date
2015-04-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative analgesia. Pain, unspecified

Interventions

Intervention 1: in group 1 paracetamol 33 mg/kg for 24 h(2g for 60 kg)and dexmedetomidine 0.15 microgram/kg/h (200 microgram) for 24h are used in total volume 100cc with normal saline and 4cc/h conti
Treatment - Drugs
in group 1 paracetamol 33 mg/kg for 24 h(2g for 60 kg)and dexmedetomidine 0.15 microgram/kg/h (200 microgram) for 24h are used in total volume 100cc with normal saline and 4cc/h continuous flow
group 2 ketorolac 1mg/kg (60 mg) for 24h and dexmedetomidine 0.15 microgram/kg/h (200 microgram) for 24h are used in total volume 100cc with normal saline and 4cc/h continuous flow

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 38 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Parturients aged between 18 and 38, elective cesarean section; American Society of Anesthesiologists (ASA) physical statuses grade I and II; Singed infomed consent; neuroaxial (spinal or epidural) anesthesia; Exclusion criteria: A history of opioid analgesic use or tranquilliser use; History of coagulopathy, Psychopatology; History of gastrointestinal problem too NSAID; American Society of Anesthesiologists (ASA) physical statuses grade more than II; Emergency cesarean section; age less than 18 and more than 38 years old; general anesthesia; dissatisfaction

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 6,12,24 h post operatie. Method of measurement: VAS.

Secondary

MeasureTime frame
Parturient satisfaction. Timepoint: 24 h. Method of measurement: parturient expression.;Sedation,nausea vomiting dizziness,bleeding. Timepoint: 6 12,24,hour. Method of measurement: ramsy sedation scor ,parturient expression.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactshiva nowruzinia

Iran University of Medical Science

snowruzinia@yahoo.comfarnadimani@yahoo.com+98 21 6435 2107

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026