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Comparison of post-operative analgesic effect of adding Dexmedetomidine or dexamethasone to lidocaine through local anastasia in forearm surgery

Comparison of post operative analgesic effect of adding Dexmedetomidine or dexamethasone to lidocaine through infraclavicular block in forearm surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016011423473N2
Enrollment
75
Registered
2016-06-06
Start date
2015-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Forearm laceration. Injury of nerves at forearm level, Injury of muscle and tendon at forearm level

Interventions

Intervention 1: In group 1, 28 cc lidocaine 1.5% plus 2cc distilled water will administer. Intervention 2: In group 2, 28 cc lidocaine 1.5% plus 8mg Dexamethasone will administer. Intervention 3: In g
Placebo
Prevention
In group 1, 28 cc lidocaine 1.5% plus 2cc distilled water will administer.
In group 2, 28 cc lidocaine 1.5% plus 8mg Dexamethasone will administer
In group 3, 28 cc lidocaine 1.5% plus 1µgr/kg Dexmedetomidine will administer.

Sponsors

Vice Chancellor for research Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients 20–60 years old; with American Society of Anesthesiologists (ASA) physical status I or II; scheduled for elective forearm surgery. Exclusion criteria: Presence of underlying diseases such as coagulopathy, peripheral vascular diseases and neuropathy; patient’s avoidance; any history of allergy to local anesthetics; treatment with palliative drugs and those affecting the CNS; addiction; neurologic deficit in respective organ; infection in the site of injection; pregnancy; BMI?20 & BMI>40; the use of drugs which interfere with lidocaine such as beta blockers, cimetidine, phenytoin.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: In 2, 4 and 6 hours after infraclavicular block. Method of measurement: Visual analogue Scales(VAS).;Total analgesic dose administered. Timepoint: During 6 hrs after the infraclavicular block ( With interval 2hrs). Method of measurement: Patient file.

Secondary

MeasureTime frame
Onset of sensory and motor block. Timepoint: From the start of anesthetics injection. Method of measurement: Evaluate the patient’s response to needle hitting on surgical site and griping force.;Time of duration of sensory block. Timepoint: The time interval between the time of loss of pain sensation at forearm to reappearance of paresthesia. Method of measurement: Pin-prick test.;Hemodynamic variables of the block. Timepoint: In 5, 10, 15, 20 and 30 minutes after infraclavicular block. Method of measurement: Monitoring system.;Time of duration of motor block. Timepoint: The time interval between the time of loss of pain sensation at forearm to complete recovery of motor function. Method of measurement: Gripping force test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hoda Shehamat

Qazvin University of Medical Sciences

hoda_shahamat@yahoo.com+98 28 3332 0105

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026