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Effect of Dexamethasone to prevent Propofol injection pain

Effect of Dexamethasone to prevent Propofol injection pain in children 6 to 13 years old in elective surgery Birjand Valiasr hospital and Emamreza hospital in 2016

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016011325992N1
Enrollment
50
Registered
2016-02-19
Start date
2016-01-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Propofol injection pain. Pain, not elsewhere classified

Interventions

Intervention 1: Study group: Injection of 0.15 micrograms per kilogram immediately before induction of anesthesia Propofol injection 20% . Intervention 2: Control group: Normal Saline at the same volu
Treatment - Drugs
Study group: Injection of 0.15 micrograms per kilogram immediately before induction of anesthesia Propofol injection 20% .
Control group: Normal Saline at the same volume confounding medication immediately before induction of anesthesia Propofol infusion dose by 20%

Sponsors

Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 13 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Children ages 6 to 13 years undergoing elective surgery (tonsillectomy, adenotonsillectomy, adenoctomy, lower extremity fractures). Exclusion criteria: included children crying when entering the operating room; emergency; abnormal liver and renal function; musculoskeletal disorders and allergy to Propofol, Dexamethasone; and also entering an intravenous line in the back of their hand are impossible.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Facial expressions child. Timepoint: Immediatly after the injection 20% of the doss of Propofol anesthesia. Method of measurement: Face Pain Scale (FPS) with rating (0 to 10).;Heart rate of patient. Timepoint: Before Dexamethasone and Normal Saline injection and after administration of anesthesia Propofol dose by 20%. Method of measurement: In bits per minute using ECG.

Secondary

MeasureTime frame
Injection site pain, redness, injection site phlebitis. Timepoint: After transferring the patient to recovery. Method of measurement: Visit the site of injection.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Hashemy

Birjand University of Medical Sciences

hossein.hashemy93@yahoo.com+98 56 3234 7548

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026