Type 2 diabetic. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group: One capsule coenzyme Q10 (100 mg) per day for 12 weeks. Intervention 2: Control group: One capsule placebo cellulose acetate (100 mg) per day for 12 weeks.
Treatment - Drugs
Sponsors
Vice Chancellor for research of Arak University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Type 2 diabetic patients for more than 2 years and not consumption of vitamin and mineral supplements during the last three months. Exclusion criteria: changing in dosage of glucose lowering medications; physical activity and diet during the intervention; any chronic renal; hepatic; thyroid; haematic; acute and chronic pancreatitis; tuberculosis; gastrointestinal disorders; using anticoagulants; diuretics and ß blockers; hormone therapy; insulin therapy; alcoholism; smoking; pregnancy and lactation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting glucose. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;Fasting insulin. Timepoint: Before and after 12 weeks of intervention. Method of measurement: ELISA.;HbA1C. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Chromatoghraphy.;TG. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;TC. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;HDL-C. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;LDL-C. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Friedewald’s equation.;Amylase. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;Adenosine deaminase. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;Catalase. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Spectrophotometric.;Antioxidant capacity. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;Q10. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Chromatoghraphy.;Lipid ratios. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Formula.;Insulin sensitivity. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Formula. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Barometer.;Waist circumference. Timepoint: Before and after 12 weeks of intervention. Method of measurement: tape measure.;BMI. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Formula. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ali Khosrowbeygi
Arak University of Medical Sciences
Outcome results
None listed