Effect of Zataria Multiflora Boiss On Ventilator Associated Pneumonia

Comparison the effect of Zataria Multiflora Boiss%0.5 oral solution and chlorhexidine on bacterial pathogens of Ventilator Associated Pneumonia ( VAP) in patient admitted in cardiac surgery intensive care unit

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016011225986N1

Enrollment

Registered

2016-03-04

Start date

2016-02-09

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia. Bacterial pneumonia, not elsewhere classified

Interventions

Intervention 1: Zataria Multiflora Boiss%0.5 oral solution three times a day up to the end of extubation. Intervention 2: Chlorhexidine 0.12% oral solution three times a day up to the end of extubat

Prevention

Zataria Multiflora Boiss%0.5 oral solution three times a day up to the end of extubation

Chlorhexidine 0.12% oral solution three times a day up to the end of extubation

Placebo( normal saline) oral solution three times a day up to the end of extubation

Eligibility

Sex/Gender

All

Age

50 Years to 70 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: patients with age between 50-70 years, who underwent open heart surgery; dentate patients; admition inintensive care unit minimum 2 days and maximum 5 days; intubation minimum 12 hours. exclusion criteria: Patients with emergent surgery; preoperative antibiotic therapy; preoperative respiratory infection; history of radiotherapy; history of corticosteroid therapy; hypersensitivity to chlorhexidine; oral mucosal lesions; advanced periodontitis; active caries; pregnancy death

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Infetion with Acinetobacter bacteria. Timepoint: at the begining of intubation, at the end of extubation. Method of measurement: Colony Count.;Infection With Enterobacter bacteria. Timepoint: at the begining of intubation, at the end of extubation. Method of measurement: Colony Count.;Infection With Pseudomonas aeruginosa. Timepoint: at the begining of intubation, at the end of extubation. Method of measurement: Colony Count.	—

Measure

Time frame

Infetion with Acinetobacter bacteria. Timepoint: at the begining of intubation, at the end of extubation. Method of measurement: Colony Count.;Infection With Enterobacter bacteria. Timepoint: at the begining of intubation, at the end of extubation. Method of measurement: Colony Count.;Infection With Pseudomonas aeruginosa. Timepoint: at the begining of intubation, at the end of extubation. Method of measurement: Colony Count.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactGhasem Faghanzadeh Ganji

Babol University of Medical Science

ghf.ganji@yahoo.com+98 11322383015

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026