The effect of lettuce seed on hyperlipidemia

Investigation the effect of hydroalcoholic extract of lettuce seed on lipid profile in hyperlipidemic patients: a randomized double blind clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016011213058N5

Enrollment

140

Registered

2016-10-25

Start date

2016-02-09

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyperlipidemia. Hyperlipidaemia, unspecified

Interventions

Intervention 1: Intervention group: Prescription of lettuce seed capsules (1000mg/ day) plus atorvastatin tablet (20mg/day) in hyperlipidemic patients for 12 weeks. Participants did not receive any ot

Treatment - Drugs

Intervention group: Prescription of lettuce seed capsules (1000mg/ day) plus atorvastatin tablet (20mg/day) in hyperlipidemic patients for 12 weeks. Participants did not receive any other hypolipidemi

Control group: prescription of placebo capsules (1000mg/ day) plus Atorvastatin tablet (20mg/day) in hyperlipidemic patients for12 week. Participants did not receive any other hypocholestrolemic drugs

Eligibility

Sex/Gender

All

Age

25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Male and female outpatients aged 25 to 65 years; incidence of hyperlipidemia with at least one of the following factors related to cholesterol > 200 mg/dl; TG> 150 mg / dl; LDL> 130 mg/dl; HDL<40 mg/dl. The exclusion criteria: the patients who had underlying diseases such as diabetes; IHD; hypertension; metabolic syndrome; peripheral vascular disease; coronary artery disease; LDL more than 190 in patients who needs medical treatment (for healthy people or with one risk factor); LDL = 160 in patients they need drug treatment (for those with two or more risk factors). Risk Factors: smoking; hypertension; low HDL level (less than 40); history of coronary artery disease at an early age in the household (less than 55 years in males and in females under age 65years old).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Cholestrol, Tg, HDL, LDL. Timepoint: Baseline, after 6th week, after 12th week. Method of measurement: Blood test.;BMI. Timepoint: Every 2 weeks. Method of measurement: Height/ weight.	—

Secondary

Measure	Time frame
Side effects. Timepoint: Every 2 weeks. Method of measurement: Questionair.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Ahmad Mohajeri

Mashhad University of Medical Sciences

mohajeria@yahoo.com+98 51 3711 2611

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026