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The effect of lycopene in the treatment of oral lichen planus

Evaluation of effectiveness of lycopen in improvement of erosive and atrophic oral lichen planus lesions

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201601113133N8
Enrollment
2
Registered
2016-04-18
Start date
2015-12-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral lichen planus. Other lichen planus

Interventions

Intervention 1: Intervention group: In this group, patients will receive topical corticosteroid in addition to lycopene, patient will use the drug 4 times a day for 2 weeks (An hour befor each meal
Treatment - Drugs
Placebo
Intervention group: In this group, patients will receive topical corticosteroid in addition to lycopene, patient will use the drug 4 times a day for 2 weeks (An hour befor each meal and 20 minutes
control group:In this group, patient will receive just topical corticosteroide and patient will to use the drug 4 times a day for 2 weeks (An hour befor each meal and 20 minutes befor sleep), and avoi

Sponsors

Vice chancellor for research,Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria:Diagnostic criteria is clinical and histopathological view of the lesions. Exclusion criteria: patients with systemic disease, skin lichen planus, drug user, pregnant wemen, smokers, patients with dysplastic lesions and lesions close to restorations and also patients receiving treatment for oral lesions was than a month ago.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Reduction in size of the lesion. Timepoint: Before starting treatment, every week for 12 weeks after starting treatment. Method of measurement: In each follow up session size of the lesion will be measured by caliper.

Secondary

MeasureTime frame
Reduced pain of the lesion. Timepoint: Before starting treatment, every week for 12 weeks after starting treatment. Method of measurement: Use of Visual Analoge Scale (VAS) from 0- 10, 0: no pain sensation and 10: severe pain sensation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Fateme Arbabi Kalati

Zahedan University of Medical Sciences

F kalati@yahoo.com+98 54 1244 1824

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026