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The effect of flaxseed oil in the treatment of non-alcoholic fatty liver

Compare the effect of flaxseed and sunflower oil on anthropometric characteristics, pressure and blood lipids and liver enzymes in patients with nonalcoholic fatty liver in overweight patients with a low-calorie diet

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016011125957N1
Enrollment
80
Registered
2016-02-07
Start date
2015-12-16
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nonalcoholic Fatty Liver. (Nonalcoholic fatty liver disease (NAFLD

Interventions

Intervention 1: The control group consisted of 40 patients. Randomly placed in this group. 20 grams per day for 3 months receive sunflower oil. Diet and recommendations are presented separately for ea
Treatment - Drugs
Treatment - Other
The control group consisted of 40 patients. Randomly placed in this group. 20 grams per day for 3 months receive sunflower oil. Diet and recommendations are presented separately for each person. The e
The intervention group consisted of 40 patients. Randomly placed in this group. 20 grams per day for 3 months receive flaxseed oil. Diet and recommendations are presented separately for each person. T

Sponsors

Oil Version Factory
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: having NAFLD by medical diagnosis (using ultrasound) ; BMI = 25 and above ; willingness to participate in the study, the absence of diabetes mellitus type 2 ;heart disease ;cardiovascular and liver disease (cirrhosis, liver disease Alcohol, viral hepatitis, autoimmune hepatitis, primary biliary cirrhosis, biliary obstruction, liver damage induced by drugs hereditary Hemochromatosis, sclerosis cholangitis and antitrypsin deficiency of a-a-1) ;other serious diseases such as cancer ;kidney failure and celiac disease, etc) ;lack of pregnancy ;lactation ;lack of drugs that are causing fatty liver (methotrexate, tamoxifen, Valproate, etc.) ;avoiding the use of any type of lipid lowering agents (atorvastatin, lovastatin, pravastatin, etc.) ;fibrates (gemfibrozil, fenofibrate) ;lack of malnutrition ;have no special diets such as vegan and vegetarian ;not drinking alcohol and having over 18 years of age. Exclusion criteria: non-compliance with recommended diet for more than 15 days over 3 months ;acute or infectious disease ;hospitalization or in cases where the criteria mentioned is.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Blood pressure. Timepoint: Before the intervention, after the intervention and the end of each month. Method of measurement: Barometer.;Lipid profile. Timepoint: Before the intervention, after intervention. Method of measurement: blood test.;Anthropometric indices. Timepoint: Before the intervention, after the intervention and the end of each month. Method of measurement: Devices BIA, scales, meters.;Liver enzymes. Timepoint: Before the intervention, after intervention. Method of measurement: blood test.;Changing in the degree of fatty liver. Timepoint: Before the intervention, after the intervention. Method of measurement: Ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDoctor Masume Akhlaghi

Department of Food Science and Nutrition

shahlarezaei13932014@gmail.com+98 71372510018

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026