Benefits of Q10 supplementation in patients with type II diabetes

Effects of Q10 supplementation on serum levels of gamma glutamyl transferase, pseudo cholinesterase, bilirubin, ferritin and C-reactive protein in patients with type II diabetes

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016011125949N1

Enrollment

Registered

2016-01-30

Start date

2016-03-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetic. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: One capsule coenzyme Q10 (100 mg) per day for 12 weeks. Intervention 2: One capsule placebo cellulose acetate (100 mg) per day for 12 weeks.

Treatment - Drugs

Placebo

One capsule coenzyme Q10 (100 mg) per day for 12 weeks.

One capsule placebo cellulose acetate (100 mg) per day for 12 weeks.

Eligibility

Sex/Gender

Female

Age

30 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Type 2 diabetic patients for more than 2 years and not consumption of vitamin and mineral supplements during the last three months. Exclusion criteria: changing in dosage of glucose lowering medications; physical activity and diet during the intervention; any chronic renal; hepatic; thyroid; haematic and gastrointestinal disorders; using anticoagulants; diuretics and ß blockers; hormone therapy; insulin therapy; alcoholism; smoking; pregnancy and lactation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Fasting glucose. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;Fasting insulin. Timepoint: Before and after 12 weeks of intervention. Method of measurement: ELISA.;HbA1C. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Chromatoghraphy.;HDL-C. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;TG. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;TC. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;LDL-C. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Friedewald’s equation.;Q10. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Chromatoghraphy.;Gamma glutamyl transferase. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;Bilirubin. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;Ferritin. Timepoint: Before and after 12 weeks of intervention. Method of measurement: ELISA.;Hs-CRP. Timepoint: Before and after 12 weeks of intervention. Method of measurement: ELISA.;Pseudo cholinesterase. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.	—

Measure

Time frame

Fasting glucose. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;Fasting insulin. Timepoint: Before and after 12 weeks of intervention. Method of measurement: ELISA.;HbA1C. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Chromatoghraphy.;HDL-C. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;TG. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;TC. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;LDL-C. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Friedewald’s equation.;Q10. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Chromatoghraphy.;Gamma glutamyl transferase. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;Bilirubin. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;Ferritin. Timepoint: Before and after 12 weeks of intervention. Method of measurement: ELISA.;Hs-CRP. Timepoint: Before and after 12 weeks of intervention. Method of measurement: ELISA.;Pseudo cholinesterase. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.

—

Secondary

Measure	Time frame
Blood pressure. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Barometer.;Waist circumference. Timepoint: Before and after 12 weeks of intervention. Method of measurement: tape measure.;BMI. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Formula.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ali Khosrowbeygi

Arak University of Medical Sciences

a.khosrowbeygi@arakmu.ac.ir; khosrowbeygi@yahoo.com+98 86 3417 3501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026