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Effect of aspirin on schizophrenia

Effect of Adding Aspirin to Antipsychotic Treatment on Severity of Symptoms in Schizophrenic Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016010725892N1
Enrollment
60
Registered
2016-02-05
Start date
2014-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia. Schizophrenia

Interventions

In addition to antipsychotic medication, intervention 1 received daily aspirin produced by Daroupakhsh Co for 6 weeks at a dose of 500 mg, while intervention 2, in addition to antipsychotic medication
Treatment - Drugs

Sponsors

Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria were age of 18-65 years old; diagnosed with schizophrenia based on clinical interview and DSM-IV-TR; patients with 2 years of history since the onset of the disease. The exclusion criteria were unwillingness to participate in the study; failure to see doctor for follow-up for whatever reason; unstable medical illness and medical history; contraindications for use of aspirin, such as asthma or seasonal allergies, ulcers, kidney disease, active bleeding or clotting of blood disorders such as hemophilia or bleeding, gout, nasal polyps; chronic use of NSAID; concomitant use of corticosteroids for any reason and maternity.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
PANSS test. Timepoint: On the first day, at the end of the sixth week and one month after cessation of aspirin or placebo. Method of measurement: PANSS test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAsefeh Mojdeh

Isfahan University of Medical Sciences

asf.mojdeh@gmail.com+98 31 3260 0599

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026