Abnormal blood-pressure reading, without diagnosis. Abnormal blood-pressure reading, without diagnosis
Conditions
Interventions
Intervention 1: 5 cc/kg crystalloid fluid is infused as the bolus, spinal anesthesia is induced and then 2cc/kg/hour of fluid is maintained, once PVI > 13 %, a 250 mL crystalloid is rapidly infused an
Treatment - Other
5 cc/kg crystalloid fluid is infused as the bolus, spinal anesthesia is induced and then 2cc/kg/hour of fluid is maintained, once PVI > 13 %, a 250 mL crystalloid is rapidly infused and repeated for e
5 cc/kg crystalloid fluid is infused as the bolus, spinal anesthesia is induced and then 4-8 mL/kg/h crystalloid fluid infusion is maintained
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients aged 18 to 50 years; American Society of anesthesiologists physical status class I and II; A body mass index (BMI) less than 30 kilograms per cubic meter. Exclusion criteria: History of systemic (cardiovascular, renal, hepatic, or vascular) disorders; Need to planned pharmacologic or mechanical cardiovascular manipulation; Needing repeated blood sampling; Failure of indirect arterial blood pressure measurement; Supplementary diagnostic information from the arterial waveform; Needing central venous pressure monitoring; Needing pulmonary artery catheterization and monitoring; Requiring transvenous cardiac pacing; Needing temporary hemodialysis; Need to aspirate air emboli; Inadequate peripheral intravenous access; Prolonged surgery (longer than 3 hours);
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total amount of intraoperative fluids infused after fluid therapy according to plethysmographic variability index (PVI). Timepoint: End of surgery. Method of measurement: Milliliter.;Amounts of lactate in fluid therapy according to PVI (plethysmographic variation Index). Timepoint: On admission as well as at the end of surgery. Method of measurement: Millimole/liter , Enzymatic.;Mean arterial pressure during fluid therapy according to PVI (plethysmographic variation index). Timepoint: before anesthesia as well as 1, 2, 3, and 5 minutes after that. Method of measurement: Using patients monitoring - millimeter of mercury.;Total amounts of Urine output after fluid therapy according to PVI (plethysmographic variation index). Timepoint: End of surgery. Method of measurement: Milliliter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total amount of intraoperative fluids infused after fluid therapy according to conventional method. Timepoint: End of surgery. Method of measurement: Milliliter.;Amounts of lactate in fluid therapy according to conventional method. Timepoint: on admission as well as at the end of surgery. Method of measurement: Millimole/liter, Enzymatic.;Mean arterial pressure during fluid therapy according to conventional method. Timepoint: Before anesthesia as well as 1, 2, 3, and 5 minutes after that. Method of measurement: Using patients monitoring - millimeter of mercury.;Total amounts of Urine output after fluid therapy according to conventional method. Timepoint: End of surgery. Method of measurement: Milliliter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Siamak Tavakoli
Dr. Shariati Hospital
Outcome results
None listed