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Effects of rapid or slow weight loss on body composition and metabolic risk factors

Effects of rapid or slow weight loss on body composition and metabolic risk factors in obese and overweight individuals

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016010424699N2
Enrollment
68
Registered
2016-05-08
Start date
2014-07-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity. Dietary counselling and surveillance

Interventions

Intervention 1: Slow weight loss: received low-calorie diets produced an energy deficit of 500–750 kilo calories per day that which reduced at least 5% of body weight over a period of 15 weeks. Interv
Treatment - Other
Slow weight loss: received low-calorie diets produced an energy deficit of 500–750 kilo calories per day that which reduced at least 5% of body weight over a period of 15 weeks.
Rapid weight loss: received low-calorie diets produced an energy deficit of 1000–1500 kilo calories per day that which reduced at least 5% of body weight over a period of 5 weeks.

Sponsors

Vice chancellor for research, Ahvaz Jundishapur University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age of 20-60; BMI= 25-40 or percentage of body fat more than 25% for men and 35% for women; don’t taking the glucose and lipid- lowering drugs; interesting in participation in research; without any metabolic disease; CHD; diabetes; without autoimmune disease; cancer; without infection disease in research; no smoking; no alcoholism; without immune system suppressor drugs 6 mounts before research; no menstrual bleeding; without any diet 3 mounts before research; no consumption multivitamin mineral supplementation 3 mounts before research; women without polycystic ovary syndrome. Exclusion criteria: metabolic; CHD; autoimmune disease and cancer; infection disease in research; smoking; alcoholism; use of immune system suppressor drugs 6 mounts before research; menstrual bleeding; diet 3 mounts before research; consumption and multivitamin mineral supplementation 3 mounts before research; women with polycystic ovary syndrome; no interesting for participation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Insulin. Timepoint: Before and after intervention. Method of measurement: ELISA - mcU/ml.;FBS. Timepoint: Before and after intervention. Method of measurement: mg/dl - Enzymatic method.;Lipid Profile. Timepoint: Before and after intervention. Method of measurement: mg/dl - Enzymatic method.;Hs-CRP. Timepoint: Before and after intervention. Method of measurement: mg/dl - ELISA.;CBC. Timepoint: Before and after intervention. Method of measurement: Automated CBC analyzer.;Urine analysis. Timepoint: Before and after intervention. Method of measurement: Enzymatic method.;Blood pressure. Timepoint: Before and after intervention. Method of measurement: Blood pressure machine.;Anthropometric tests. Timepoint: Before and after intervention. Method of measurement: Body fat Analyzer.;Resting metabolic rate. Timepoint: Before and after intervention. Method of measurement: Indirect calorimetry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDamoon Ashtary-Larky

Ahvaz Jundishapur University of Medical Sciences

damoon_ashtary@yahoo.com+98 614436106

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 26, 2026