Delivery pain and its effect on fetal health condition. Fetus and newborn affected by maternal anaesthesia and analgesia in pregnancy, labour and delivery
Conditions
Interventions
Intervention 1: Neuraxial method: during delivery 25 to 50 microgram intrathecal fentanyl injection as opioid combined with 2.5 milligram bupivacaine to enhance analgesia quality and duration. Interve
Prevention
Neuraxial method: during delivery 25 to 50 microgram intrathecal fentanyl injection as opioid combined with 2.5 milligram bupivacaine to enhance analgesia quality and duration
Control group: vaginal delivery will be performed without intrathecal opioid injection.
Sponsors
Vice Chancellor for Research of Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: There is a possibility of natural birth; There is labor pain and active delivery phase; mother's consent to reduce delivery pain; spouse consent. Exclusion criteria: mother's disinclination to participate; Inability to maintain immobility during procedure; Coagulation disorders and defects in homeostasis; Increased intracranial pressure for any reason; Frank infection at the needle site; Hypersensitivity to local anesthetics or other medications using in this methods; Acute lesions of the central nervous system; Maternal hemodynamic instability (hypovolemia, hypotension); Heart diseases that cardiac output is severely limited; fetal distress.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: before the intervention, Immediately after the intervention, Every 5 minutes until delivery, Immediately after delivery. Method of measurement: visual analogue scale tool.;Apgar. Timepoint: first, fifth and tenth minutes after birth. Method of measurement: Apgar scoring system.;Fetal heart rate. Timepoint: before the intervention, Immediately after the intervention, Every 5 minutes until delivery, Immediately after delivery. Method of measurement: physical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypotention. Timepoint: before the intervention, immediately after the intervention, every 5 minutes until delivery, immediately after delivery. Method of measurement: Sphygmomanometer tool.;Oxygen saturation level. Timepoint: before the intervention, immediately after the intervention, every 5 minutes until delivery, immediately after delivery. Method of measurement: pulse oximeter.;The first time of breadtfeeding. Timepoint: Immediately after delivery. Method of measurement: Physical examination.;Pain. Timepoint: before the intervention, immediately after the intervention, every 5 minutes until delivery, immediately after delivery. Method of measurement: visual analogue scale tool. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHassan Soleiman Pour
Medicine faculty
Outcome results
None listed