Disturbance of activity and attention. Disturbance of activity and attention
Conditions
Interventions
Intervention 1: Tablet L- carnosine 400 mg BID and Ritaline 0.5 to 1.5 mg per day as intervention group for 8 weeks. Intervention 2: Ritaline 0.5 to 1.5 mg per day and placebo as control group for 8 w
Treatment - Drugs
Placebo
Tablet L- carnosine 400 mg BID and Ritaline 0.5 to 1.5 mg per day as intervention group for 8 weeks
Ritaline 0.5 to 1.5 mg per day and placebo as control group for 8 weeks
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
6 Years to 17 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: diagnosis of ADHD based on DSM-5; age between 6-17 years old. Exclusion criteria: mental retardation; receiving of L carnosine during the last 3 weeks; presence of any psychiatric disorders except for ODD; history of allergy to L carnosine or Ritaline; presence of any medical problem including cardiovascular diseases; presence of uncontrolled seizures; systolic blood pressure more than 120 mm Hg; resting pulse rate less than 60/minute or more than 115/minute; receiving any supplement or medication for ADHD.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of ADHD. Timepoint: Week 0 (before treatment) and Weeks 4 and 8 after treatment. Method of measurement: Teacher and Parent ADHD Rating Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactProf. Shahin Akhondzadeh
Tehran University of Medical Sciences
Outcome results
None listed