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Conditions
Interventions
Intervention 1: Intervention: administration of propolis , oral solution ,5 dropsTDS(16mg TDS), duration of intervention is one month. Intervention 2: Control group receives placebo.
Prevention
Placebo
Intervention: administration of propolis , oral solution ,5 dropsTDS(16mg TDS), duration of intervention is one month
Control group receives placebo
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients undergoing the first episode of head and neck radiotherapy without any oral mucositis.Exclusion criteria: Chronic liver failure (Stage II & III); Chronic kidney disease (Stage IV & V); oral active infection; active collagen vascular disease; presence of any type of allergy and sensitivity to honey and propolis.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mucositis severity. Timepoint: weekly. Method of measurement: Based on the criteria of NCI, OMAS & WHO. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Once a week for a month. Method of measurement: Based on the pain scale grade classification(0-10).;Dysphagia. Timepoint: Once a week for a month. Method of measurement: Clinical evaluation and Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamaneh Dodge
Shahid Beheshti University of Medical Sciences
Outcome results
None listed