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effects of Bromocriptine and Metformin on polycystic ovary syndrome

Comparison of the effects of Bromocriptine and Metformin on the treatment of menstrual pattern in young women with polycystic ovary syndrome

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201512313461N7
Enrollment
64
Registered
2016-03-16
Start date
2015-12-31
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Group 1 : 5 mg of bromocriptine daily is administered . In the first week 1.25 mg and after that 1.25 mg weekly is added until 5 mg per day. Intervention 2: Group 2 : a daily dose of 1
Treatment - Drugs
Group 1 : 5 mg of bromocriptine daily is administered . In the first week 1.25 mg and after that 1.25 mg weekly is added until 5 mg per day.
Group 2 : a daily dose of 1000 mg of metformin is administered. In the first week 250 mg and after that 250 mg weekly is added until to 2 pills a day.

Sponsors

?Vice chancellor for research, Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : menstrual cycles greater than 40 days; acnea; hirsutism; pco on sonography; LH/FSH ratio greater than 2; normal prolactin; normal TSH; excess androstenedione; normal blood sugar. Exclusion criteria: marriage; psychiatric drug users; professional athletes; primary amenorrhea; history of chronic illnesses; body mass index greater than 30 kg/m2.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Menstrual pattern. Timepoint: Before , 3 and 6 months after intervention. Method of measurement: Questionnaire, menstrual cycle days measurement.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFiroozeh Veisi

Vice chancellor for research, Kermanshah University of Medical Sciences, Kermanshah, Iran

firoozehveisi@yahoo.com+98 83 3427 6309

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026