Termination of pregnancy in the second trimester. Medical abortion
Conditions
Interventions
Intervention 1: In the experimental group letrozole tablets orally at a dose of 2 .5 mg in the form of two tablets given every 12 hours for two days. At the beginning of the third day Misoprostol tabl
Treatment - Drugs
In the experimental group letrozole tablets orally at a dose of 2 .5 mg in the form of two tablets given every 12 hours for two days. At the beginning of the third day Misoprostol tablets at a dose of
The control group will receive 8 placebo tablets on two consecutive days , 2 tablets every 12 hours given. Then on the third day, vaginal misoprostol of 100 micrograms as a 4 tablets every 6 hours wi
Sponsors
Vice chancellor for research, Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Gestational age of 13 to 22 with an indication for termination of pregnancy in medical method; Chorioamionitic. Exclusion criteria: Patients with a history of caesarean section; Maternal serious chronic systemic and chronic disease; Cardiovascular disease.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of induction to abortion. Timepoint: From admission until 48 hours later. Method of measurement: Doctor observation.;Blood pressure. Timepoint: Baseline, every 2 hours, discharge time. Method of measurement: Manometer.;Heart rate. Timepoint: Baseline, every 2 hours, discharge time. Method of measurement: By doctor.;Temperature. Timepoint: Baseline, every 2 hours, discharge time. Method of measurement: By thermometer. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed