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Evaluation of the protective effect of Curcuma Longa induced nephrotoxicity in patients with cancer

Evaluation of the protective effect of Curcuma Longa against cisplatin induced nephrotoxicity in patients with cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151228025732N70
Enrollment
30
Registered
2021-12-07
Start date
2021-12-06
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cisplatin induced nephrotoxicity. Acute kidney failure, unspecified

Interventions

Intervention 1: Intervention group: In addition to routine treatments, this group consumes one turmeric tablet of "Dineh Iran" company (Each tablet contains 450 mg of turmeric rhizome powder and 50 mg

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18-60 years Confirmation of cancer by a specialist doctor The disease should be such that the use of cisplatin as a treatment is approved by a specialist doctor

Exclusion criteria

Exclusion criteria: The patient has a previous kidney disease (GFR is low from the beginning) Existence of underlying diseases such as diabetes, hypertension, etc. in the patient Increased creatinine indicated for discontinuation of the drug

Design outcomes

Primary

MeasureTime frame
Blood creatinine level. Timepoint: Before starting treatment with Cisplatin and 5 and 21 days after starting treatment with Cisplatin. Method of measurement: Biorexfars Laboratory Diagnostic Kit.;BUN(Blood Urea Nitrogen) level. Timepoint: Before starting treatment with Cisplatin and 5 and 21 days after starting treatment with Cisplatin. Method of measurement: Biorexfars Laboratory Diagnostic Kit.;Creatinine Clearance level. Timepoint: Before starting treatment with Cisplatin and 5 and 21 days after starting treatment with Cisplatin. Method of measurement: Through Up-to-date software and using the CKD-EPI formula.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Amir Sarabi

Semnan University of Medical Sciences

are20935@gmail.com+98 23 3345 1336

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026