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A study on melatonin and Vitamin C and zinc efficacy in patients with COVID19

A study on melatonin and Vitamin C and zinc efficacy in patients with COVID19 hospitalized in intensive care unit of Semnan Kowsar Hopsital

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151228025732N52
Enrollment
30
Registered
2020-04-09
Start date
2020-04-07
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid-19. Covid-19 infection

Interventions

Intervention 1: Intervention group: In addition to national protocol medications, patients receive 40 mg of melatonin (Simorgh Pharmaceutical Company)
(2 tablets, 5 mg every 6 hours) via NG tube. Patients will also receive 2 grams of ascorbic acid per day at 5% dextrose(Daropakhsh Company) every 6 hours, plus 220 mg of sulfate every 6 hours(Alhawi C

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 65 Years

Inclusion criteria

Inclusion criteria: Patients with Covid 19 Conscious consent of the patient

Exclusion criteria

Exclusion criteria: Malignant diseases Severe renal, hepatic failure History of drug allergy

Design outcomes

Primary

MeasureTime frame
Number of breaths per minute. Timepoint: Before the intervention, from the start of treatment to the patient's recovery. Method of measurement: Vital signs monitoring devices.;The rate of decline of lung infection. Timepoint: Before the intervention, from the start of treatment to the patient's recovery. Method of measurement: Clinical examination, if necessary, radiography or CT scan.;The course of the disease. Timepoint: Before the intervention, from the start of treatment to the patient's recovery. Method of measurement: Clinical examination, if necessary, radiography or CT scan.;Heart rate. Timepoint: Before the intervention, from the start of treatment to the patient's recovery. Method of measurement: Vital signs monitoring devices.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahboubeh Darban

Semnan University of Medical Sciences

are20935@gmail.com+98 23 3345 1336

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 24, 2026