Effect of vitamin D supplementation on controlling blood sugar in patients with gestational diabetes

A clinical trial to investigate the effect of vitamin D supplementation on glucose status in mothers with gestational diabetes

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015122725725N1

Enrollment

Registered

2016-01-08

Start date

2015-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational diabetes. Diabetes mellitus in pregnancy

Interventions

Intervention 1: In intervention group: oral vitamin D (50000 IU) every two weeks is given for three doses. Intervention 2: control group: they do not receive any supplemental vitamin D.

Treatment - Drugs

In intervention group: oral vitamin D (50000 IU) every two weeks is given for three doses

control group: they do not receive any supplemental vitamin D

Eligibility

Sex/Gender

Female

Age

17 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: women over 18 year-old; gestational age of 18 to 13 week. Exclusion criteria: kidney or hepatic failure; alcoholism; malabsorption; hypo or hyperparathyroidism; malignancies; consumption of drugs affecting vitamin D metabolism; using vitamin D supplements; history of diabetes.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
HbA1c level. Timepoint: two weeks after the last dose of Vitamin D. Method of measurement: BLOOD TEST.;FBS (fasting blood sugar). Timepoint: two weeks after the last dose of Vitamin D. Method of measurement: BLOOD TEST.;INSULIN LEVEL IN BLOOD. Timepoint: two weeks after the last dose of Vitamin D. Method of measurement: BLOOD TEST.;Insulin resistance. Timepoint: two weeks after the last dose of Vitamin D. Method of measurement: Homeostasis model assessment (HOMA-IR).	—

Measure

Time frame

HbA1c level. Timepoint: two weeks after the last dose of Vitamin D. Method of measurement: BLOOD TEST.;FBS (fasting blood sugar). Timepoint: two weeks after the last dose of Vitamin D. Method of measurement: BLOOD TEST.;INSULIN LEVEL IN BLOOD. Timepoint: two weeks after the last dose of Vitamin D. Method of measurement: BLOOD TEST.;Insulin resistance. Timepoint: two weeks after the last dose of Vitamin D. Method of measurement: Homeostasis model assessment (HOMA-IR).

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Secondary

Measure	Time frame
IUFD (intrauterine fetal death). Timepoint: during pregnancy. Method of measurement: sonography.;IUGR (Intrauterine growth restriction). Timepoint: during pregnancy. Method of measurement: sonography.;LGA (Large for gestational age). Timepoint: during pregnancy. Method of measurement: sonography.;Preeclampsia. Timepoint: during pregnancy. Method of measurement: Examination.;Premature birth. Timepoint: during pregnancy. Method of measurement: Examination.;Vitamin D level of umbilical cord. Timepoint: after birth. Method of measurement: Diazon kit.	—

Measure

Time frame

IUFD (intrauterine fetal death). Timepoint: during pregnancy. Method of measurement: sonography.;IUGR (Intrauterine growth restriction). Timepoint: during pregnancy. Method of measurement: sonography.;LGA (Large for gestational age). Timepoint: during pregnancy. Method of measurement: sonography.;Preeclampsia. Timepoint: during pregnancy. Method of measurement: Examination.;Premature birth. Timepoint: during pregnancy. Method of measurement: Examination.;Vitamin D level of umbilical cord. Timepoint: after birth. Method of measurement: Diazon kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactTAYEBEH NADERI

Kerman University of Medical Sciences

t_NADERI@KMU.AC.IR+998 3432235011

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026