Depression. Mild depressive episode, Moderate depressive episode
Conditions
Interventions
Intervention 1: Intervention group 1: One citalopram pill with 20 miligram dose every day. Intervention 2: Intervention group 2: Combinatory product based on Echium amoenum in syrup form with 30 milil
Treatment - Drugs
Intervention group 1: One citalopram pill with 20 miligram dose every day
Intervention group 2: Combinatory product based on Echium amoenum in syrup form with 30 mililitre dose per day, two times a day
Sponsors
Vice Chancellor for research of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients are enrolled with age more than 18 years and major depression based on DSM-5 criteria. Exclusion criteria: Depression with psychotic symptoms; Having a history of bipolar disorder; Having suicidal thoughts and any plans to do so; People with a history of recent emotional trauma; Patient dependence on chemical antidepressants; Pregnant and lactating women; Sensitivity to the citalopram; Sensitivity to herbal components of combinatory product; Addiction to alcohol and narcotics
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Depression. Timepoint: Every 4 weeks. Method of measurement: Hamilton Depression Rating Scale. | — |
Primary
| Measure | Time frame |
|---|---|
| Sleep. Timepoint: Every 4 weeks. Method of measurement: Clinical interview. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mahdi Eslami
Mashhad University of Medical Sciences
Outcome results
None listed