Effect of clonidine in reducing blood pressure in hypertensive urgency situation

Comparison of clonidine and captopril effects in reducing blood pressure in hypertensive urgency situation in 2016

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015122713828N7

Enrollment

Registered

2016-05-27

Start date

2016-04-12

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension. Hypertensive diseases

Interventions

Intervention 1: Intervention 1: Clonidine 0.1 mg/ orally / stat. Intervention 2: Intervention 2: Captopril 25 mg/ sub lingual/ stat.

Treatment - Drugs

Intervention 1: Clonidine 0.1 mg/ orally / stat

Intervention 2: Captopril 25 mg/ sub lingual/ stat

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: emergency hypertension; patients' agreement to participate. Exclusion criteria: end organ damage; patients' non compliance; allergy to Clonidine or Captopril.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
High Blood Pressure. Timepoint: 15 minutes after treatment. Method of measurement: Sphygmomanometer.;Blood pressure. Timepoint: 15 min after treatment. Method of measurement: Sphygmomanometer.	—

Secondary

Measure	Time frame
Dry mouth. Timepoint: 15 min after intervention. Method of measurement: Examination.;Headache. Timepoint: 15 min after intervention. Method of measurement: Examination.;Dizziness. Timepoint: 15 min after intervention. Method of measurement: Examination.;Palpitation. Timepoint: 15 min after intervention. Method of measurement: Examination.;Cough. Timepoint: 15 min after intervention. Method of measurement: Examination.;Angioedema. Timepoint: 15 min after intervention. Method of measurement: Examination.	—

Measure

Time frame

Dry mouth. Timepoint: 15 min after intervention. Method of measurement: Examination.;Headache. Timepoint: 15 min after intervention. Method of measurement: Examination.;Dizziness. Timepoint: 15 min after intervention. Method of measurement: Examination.;Palpitation. Timepoint: 15 min after intervention. Method of measurement: Examination.;Cough. Timepoint: 15 min after intervention. Method of measurement: Examination.;Angioedema. Timepoint: 15 min after intervention. Method of measurement: Examination.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ahmad Mirdamadi

Medical School, Islamic Azad University, Najafabad Branc

drsamirdamadi@yahoo.com/+98 31 1223 8028

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026