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Evaluation of the effects of propolis- echinacea supplementation on Chronic fatigue syndrome and quality of life in lung cancer patients (NSCLC) consuming Pemetrexed

Evaluation of the effects of propolis- echinacea supplementation on Chronic fatigue syndrome and quality of life in lung cancer patients (NSCLC) consuming Pemetrexed

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151227025726N33
Enrollment
40
Registered
2023-05-20
Start date
2023-06-05
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer (NSCLC). Malignant neoplasm of unspecified part of bronchus or lung

Interventions

Intervention group: Novohil drug manufactured by Faran Chemical Factory with a dose of 450 mg (containing 400 mg of propolis and 50 mg of echinacea) is administered orally to patients twice a day for

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Lung cancer patients (NSCLC) consuming Pemetrexed

Exclusion criteria

Exclusion criteria: Patients who are allergic to medicine Patients with hypothyroidism Patients using hypnotics and neuroleptics Patients addicted to drugs Suffering from underlying nerve disorders Patients who need surgery Pregnant and lactating

Design outcomes

Secondary

MeasureTime frame
Hospitalization rate. Timepoint: Before intervention and one month after the end of intervention. Method of measurement: Patient’s record.;Rate of infection. Timepoint: Before intervention and one month after the end of intervention. Method of measurement: Patient’s record.

Primary

MeasureTime frame
Quality of life score based on EQ-5D-3L questionnaire. Timepoint: Measuring the quality of life based on the EQ-5D-3L questionnaire on days 0 and 28. Method of measurement: EQ-5D-3L questionnaire.;Fatigue complication score based on BFI questionnaire. Timepoint: Measurement of fatigue complication score based on BFI questionnaire on days 0-7-14-21-28. Method of measurement: BFI questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirreza rahimi

Shahid Beheshti University of Medical Sciences

Rahimi.amir2000@gmail.com+98 21 8820 0118

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026