Chronic Thrombo Embolic Pulmonary Hypertension(CTEPH). Chronic Thromboembolic Pulmonary Hypertension.
Conditions
Interventions
Intervention 1: Intervention group: For the intervention group, rivaroxaban was prescribed at a dose of 15 mg twice a day for 21 days and then 20 mg once a day.In the study, Rivaoxaban made by Dr. Abi
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients undergoing endarterectomy following chronic thromboembolic pulmonary hypertension at Masih Daneshvari Hospital.
Exclusion criteria
Exclusion criteria: Any allergies to the prescribed medication Any bleeding includes active gastrointestinal, pulmonary, genitourinary bleeding Cerebral aneurysm Intracranial bleeding Aneurysm and aortic dissection A patient undergoing spinal puncture Blood dyscrasia Uncontrolled blood pressure (110/180 mmHg <pressure) Inflammation and pericardial effusion Bacterial endocarditis Pregnancy and lactation Liver disease(child pugh B&C) GFR<30 mL/min Any coagulation disorder If the patient has been prescribed strong Cyp450 and Pgp inhibitors such as ketoconazole, itraconazole, posaconazole and ritonavir.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence of thrombosis. Timepoint: Patients are evaluated at one, three and six months after surgery. Method of measurement: Medical record.;Incidence of ischemic and hemorrhagic stroke. Timepoint: Patients are evaluated at one, three and six months after surgery. Method of measurement: Medical record. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of bleeding. Timepoint: Patients are evaluated at intervals of one, three and six months after surgery. Method of measurement: Medical record.;Patient readmission. Timepoint: Patients are evaluated at intervals of one, three and six months after surgery. Method of measurement: Medical record. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHossein Amini Ebrahimabad
Shahid Beheshti University of Medical Sciences
Outcome results
None listed