Acute kidney injury. Acute kidney injury
Conditions
Interventions
Intervention 1: Intervention group: Patients in the acetazolamide group are treated with acetazolamide at a dose of 500 mg once daily on the morning of surgery. Intervention 2: Control group: Patients
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: It will be performed on patients who refer to Masih Daneshvari and Modares Hospital for Coronary Artery Bypass Surgery (CABG).
Exclusion criteria
Exclusion criteria: History of any allergies to any of the compounds in acetazolamide tablets and sulfonamide compounds Liver failure (stage II, III or liver enzymes more than 3 times) Chronic renal failure (Stage IV & V CKD) or patients with serum creatinine less than 30 ml / min, anorexia Chronic heart failure (Ejection Fraction <30) Patients undergoing CABG surgery for emergency reasons. Hypokalemia (potassium less than 3.3 mmol / L), hyponatremia (sodium less than 135 mmol / L) Gout attack
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Creatinine plasma LEVEL. Timepoint: Before surgery and daily for up to seven days. Method of measurement: ELISA.;Volume of urine. Timepoint: Before the operation until the patient is in the intensive care unit. Method of measurement: The amount of urine in the urine bag. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGolnaz Afzal
Shahid Beheshti University of Medical Sciences
Outcome results
None listed