Acute Kidney Injury. Postprocedural (acute) (chronic) kidney failure
Conditions
Interventions
Intervention 1: Intervention group: administration of ubiquinone oral tablets, 300 mg, 2 times a day (every 12 hours), for 2 days (48 hours before surgery). Intervention 2: Control Group: will not rec
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patients who are candidates for Coronary Artery Bypass Graft surgery in Masih Daneshvari Hospital
Exclusion criteria
Exclusion criteria: History of hypersensitivity reaction to ubiquinone Chronic liver failure (Stage II & III) Chronic kidney disease (Stage IV & V) or patients with Glomerular Filtration Rate of lower than 30 ml/min Patient with INR of more than 2.5 Patients who receive anti-inflammatory agents at least two weeks before admission Patients who undergo emergency CABG.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute Kidney Injury. Timepoint: before surgery and 6 & 24 hours after surgery. Method of measurement: Evaluation of NGAL kits. | — |
Secondary
| Measure | Time frame |
|---|---|
| Checking of inflammatory biomarkers. Timepoint: before surgery and 24 hours after surgery. Method of measurement: Evalution of CRP kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Jahangirifard
Masih Daneshvari Hospital
Outcome results
None listed