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Efficacy of nortriptyline and duloxetine for diabetic neuropathy

Efficacy of nortriptyline and duloxetine for diabetic neuropathy type 2

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201512265692N8
Enrollment
80
Registered
2016-02-24
Start date
2016-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabet. Diabetes mellitus

Interventions

Intervention 1: Intervention Group: nortriptyline, 25 mg tablets(Pharmaceutical Amin),Daily for 35 nights with a number Doluxetine placebo for 35 nights. Intervention 2: control Group: Doluxetine, cap
Treatment - Drugs
Intervention Group: nortriptyline, 25 mg tablets(Pharmaceutical Amin),Daily for 35 nights with a number Doluxetine placebo for 35 nights
control Group: Doluxetine, capsules 20 mg(Pharmaceutical Amin),Daily for 35 nights with a number nortriptyline placebo one night for 35 nights

Sponsors

Vice Chancellor for research- Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients over 18 years of age and At least three years have passed since the risk of diabetes and with pdn (painful diabetic neuropathy)For at least a month are. exclusion criteria: patients with epilepsy, htn uncontrolled and chronic liver disease or renal failure and patients treated for other causes pain in another part of their body.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Neuropathic pain. Timepoint: Before the intervention, the duration of the intervention for 35 days, at the end of intervention. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Possible side effects of each drug. Timepoint: During the study period and at the end of the study. Method of measurement: According to Patients.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Ali Bayani

Babol University of Medical Sciences

internalmedbabol@gmail.comfadaeefarshad@gmail.comm.bayani@mubabol.ac.ir+98 11 3223 8284

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026