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Lumbar epidural injections in chronic pain management

Comparison of Epidural injection of Methylprednisolon, Bupivacaine, and Normal saline on Management of Chronic Low back Pain due to Iumbar Disc Herniation at a level

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015122625702N1
Enrollment
88
Registered
2016-03-24
Start date
2015-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic lumbar pain. Other obstetric conditions, not elsewhere classified

Interventions

Intervention 1: In the first group would be injected 80 mg of methylprednisolone Preparation of ten cc in volume into the epidural space of . Intervention 2: In the second group of local anesthetic bu
Treatment - Drugs
In the first group would be injected 80 mg of methylprednisolone Preparation of ten cc in volume into the epidural space of .
In the second group of local anesthetic bupivacaine 10 ml 0.5% into the epidural space
In the third group would be injected 10 ml of normal saline solution into epidural space

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with low back pain; does not respond to rest and medication, systemic therapy. Exclusion criteria: a history of cerebrovascular accidents and diseases; taking anti psychotic drugs; drug Abuse; patients with spinal stenosis; any bleeding areas prohibited for spinal anesthesia; unwillingness to participate in the study; indication for lumbar disc surgery; the history of back pain due to disc herniation; ; low back pain due to Sacro iliac joint problems or rheumatic diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Oswestry disability scale. Timepoint: The end of the first week, second, third, fourth and third month. Method of measurement: Questioning and examination.;Intensity of pain. Timepoint: The end of the first week, second, third, fourth and third month. Method of measurement: Observation and clinical examination.

Secondary

MeasureTime frame
Bleeding. Timepoint: 24 hours after intervention. Method of measurement: Clinical examination.;Dora tear. Timepoint: At the same time injection. Method of measurement: Observation at the time of injection.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Naghi Abeddini

Tabriz University of Medical Sciences

naghi26@yahoo.com+98 41 3389 3336

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026