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Comparison of the efficacy of Spironolcatone 5% and Progesterone 2% on hair density and diameter in female pattern hair loss

Comparison of the efficacy of Spironolcatone 5% and Progesterone 2% on hair density and diameter in female pattern androgenetic alopecia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT201512252581N4
Enrollment
36
Registered
2016-12-14
Start date
2015-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female pattern andrpgenetic alopecia. Androgenic alopecia

Interventions

Intervention 1: Control group
Topical 2% Progesterone solution, twice a day for 24 weeks. Intervention 2: Intervention group
Topical 5% Spironolactone solution, twice a day for 24 weeks.
Treatment - Drugs
Control group
Topical 2% Progesterone solution, twice a day for 24 weeks
Intervention group
Topical 5% Spironolactone solution, twice a day for 24 weeks

Sponsors

Vice Chancellor for research, Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: female; grade 1 or 2 androgenetic alopecia; no underlying hormonal disorders Exclusion criteria: patient's decision to exit the study; underlying hormonal disorder; anemia; use of topical medications in the past week; taking oral medications in the past four weeks; have allergy to spironolactone or progesterone; pregnancy or planning to pregnancy or breastfeeding

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hair density per squared cm, Hair diameter. Timepoint: At baseline, 8th, 16th ,24th weeks. Method of measurement: Trichoscopy.

Secondary

MeasureTime frame
Side effects. Timepoint: At baseline, 8th, 16th and 24th weeks. Method of measurement: Qualitative.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHerizchi ghadim Hamideh

Tabriz University of Medical Siences

drherizchi@yahoo.con+98 41 3540 6612

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026