Condition 1: Periodontitis. Condition 2: Rheumatoid arthritis. Chronic periodontitis Rheumatoid arthritis, unspecified
Conditions
Interventions
Interventions: At first, DAS-28 questionnaire filled and if periodontitis confirmed by dentist, treatment initiated which is includes non surgical scaling, root planning, systemic antibiotics (metroni
Treatment - Other
Sponsors
Semnan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: 18 years and older; diagnosis of RA at least one year ago; disease activity score between 3.2 and 5.1; having at least six natural teeth; the patient be educable; having gingivitis with mild to moderate degree. The exclusion criteria were: risk of infection; serious liver or kidney diseases; chronic infectious disease that needs to frequent use of antibiotics; uncontrolled diabetes; taking anti-thrombotic and biologic therapy; sensitivity to chlorhexidine gluconate (oral rinse); contraindication of amoxicillin and metronidazole; severe oral problems which requiring immediate surgery; pregnancy, breast-feeding or if want to get pregnant during the study period; any febrile or chronic diseases.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rheumatoid arthritis activity. Timepoint: Before initiation of interventions, 45 and 90 days after intervention. Method of measurement: DAS-28 questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Erythrocyte Sedimentation Rate. Timepoint: Before initiation of interventions, 45 and 90 days after intervention. Method of measurement: Laboratory test.;C- reactive protein. Timepoint: Before initiation of interventions, 45 and 90 days after intervention. Method of measurement: Laboratory test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Jamileh Moghimi
Semnan University of Medical Sciences
Outcome results
None listed