Condition 1: Upper or Lower limb fracture. Condition 2: Upper or Lower limb dislocation. Fracture of upper limb, level unspecified, Fracture of lower limb, level unspecified Dislocation, sprain and strain of unspecified joint and ligament of upper limb or lower limb, level unspecified
Conditions
Interventions
Intervention 1: Intervention1 (case group): In Group A, patients receive a dose of 0.25 mg / kg iv ketamine. Drugs’ dose are calculated based on patient weight. Pain severity base on visual analog sco
Treatment - Drugs
Intervention1 (case group): In Group A, patients receive a dose of 0.25 mg / kg iv ketamine. Drugs’ dose are calculated based on patient weight. Pain severity base on visual analog score (VAS) and com
Intervention2 (case group): In Group B, patients receive a dose of 0.1 mg / kg iv morphine. Drugs’ dose are calculated based on patient weight. Pain severity base on visual analog score (VAS) and comp
Sponsors
Vice chancellor for research,Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 55 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients with isolated trauma with fracture in the upper or lower extremities; aged between 15 and 55 years old; with Visual Analogue Scale pain score of more than 50 mm. Exclusion criteria: Patient’s refusal to participate in the study; having an underlying medical condition such as migraine, cardiac ischemia, schizophrenia, history of allergy to opiates or ketamine, head trauma or loss of consciousness; blood pressure of more than 180/100; vital signs Instability before and during the study; pregnancy; any inability to express their pain during the study; presence of other trauma.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain severity. Timepoint: 0, 5th,10th, 20th minute. Method of measurement: Visual analog scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dizziness, nausea, burning throat, amnesia, headache,. Timepoint: Before intervention, 5, 10 and 20 minutes after intervention. Method of measurement: physical examination.;Need for rescue analgesia. Timepoint: 20 minutes after intervention. Method of measurement: Visual analog scale of pain. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRamin Parvizrad
Arak University of Medical Sciences
Outcome results
None listed