Evaluation the effectiveness pomegranate peel extract in treatment of gingival inflammation

Evaluation the effectiveness of oral gel containing pomegranate peel extract in treatment of periodontitis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20151222025649N6

Enrollment

Registered

2018-10-20

Start date

2019-01-21

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Moderate to severe chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Intervention group: The pomegranate peel extract gel in a periodontal pocket in a selected dental quadrant. After scalling all of the teeth with a piezoelectroscopic device in a pre-s

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients with chronic periodontitis that are healthy in terms of systemicity No history of hypersensitivity

Exclusion criteria

Exclusion criteria: Receive other treatments Tobacco and alcohol consumption Pregnant and nursing women Use of orthodontic appliance

Design outcomes

Primary

Measure	Time frame
Pocket depth. Timepoint: Before intervention, one month after intervention, three months after intervention. Method of measurement: Measuring the distance of pocket base to the gingival with periodontal probe.;Clinical attachment loss. Timepoint: Before intervention, one month after intervention, three months after intervention. Method of measurement: Measuring the distance of base of pocket from CEJ.;Gingival index. Timepoint: Before intervention, one month after intervention, three months after intervention. Method of measurement: Determination gingival inflammatory conditions based on observation and comparison.;Plaque index. Timepoint: Before intervention, one month after intervention, three months after intervention. Method of measurement: Colored surfaces of tooth by disclosing agent.;Bleeding index. Timepoint: Before intervention, one month after intervention, three months after intervention. Method of measurement: Determination of inflammatory conditions and gingival hemorrhage during probingwith periodontal probe.	—

Measure

Time frame

Pocket depth. Timepoint: Before intervention, one month after intervention, three months after intervention. Method of measurement: Measuring the distance of pocket base to the gingival with periodontal probe.;Clinical attachment loss. Timepoint: Before intervention, one month after intervention, three months after intervention. Method of measurement: Measuring the distance of base of pocket from CEJ.;Gingival index. Timepoint: Before intervention, one month after intervention, three months after intervention. Method of measurement: Determination gingival inflammatory conditions based on observation and comparison.;Plaque index. Timepoint: Before intervention, one month after intervention, three months after intervention. Method of measurement: Colored surfaces of tooth by disclosing agent.;Bleeding index. Timepoint: Before intervention, one month after intervention, three months after intervention. Method of measurement: Determination of inflammatory conditions and gingival hemorrhage during probingwith periodontal probe.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoome Eivazi

Kermanshah University of Medical Sciences

m.eivazi@kums.ac.ir+98 83 3722 2400

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026